An Engineered Rare Codon Device for Optimization of Metabolic Pathways
نویسندگان
چکیده
منابع مشابه
An Engineered Rare Codon Device for Optimization of Metabolic Pathways
Rare codons generally arrest translation due to rarity of their cognate tRNAs. This property of rare codons can be utilized to regulate protein expression. In this study, a linear relationship was found between expression levels of genes and copy numbers of rare codons inserted within them. Based on this discovery, we constructed a molecular device in Escherichia coli using the rare codon AGG, ...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2016
ISSN: 2045-2322
DOI: 10.1038/srep20608